2-Methylbutyl 2-methylbutanoate

CAS:
2445-78-5
Family:
aliphatic ester
Also:
2-Methylbutyl 2-methylbutanoate, 2-methylbutyl 2-methylbutyrate, FEMA 3359, butanoic acid, 2-methyl-, 2-methylbutyl ester

Found heavily in (3 oils total)

Recorded sensory reference values
  • Affect valence: 0.6
  • Affect arousal: 0.3

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

2-Methylbutyl 2-methylbutanoate is a branched-chain fruity ester used in flavor and fragrance work and found naturally in several plants and some essential oils, including Cape chamomile. It is usually described with apple, berry, pineapple, and green-fruity nuances. The archive has good identity and occurrence coverage for this molecule, but direct wellness or mechanistic literature is sparse, so most constituent-level interpretation should stay focused on aroma chemistry and semiochemical ecology.

Aroma and practical use

fruityappleberrypineapplegreenwaxy
  • Use the recorded fruity, apple, berry, pineapple, green, waxy descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

A 2024 Springer field study identified 2-methylbutyl 2-methylbutanoate as a male-specific volatile in Clavigralla elongata, and GC-EAD assays showed antennal detection by male and female bugs as well as the parasitoid Gryon fulviventris.

A 2024 Springer field study identified 2-methylbutyl 2-methylbutanoate as a male-specific volatile in Clavigralla elongata, and GC-EAD assays showed antennal detection by male and female bugs as well as the parasitoid Gryon fulviventris.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

The same study reported that pheromone-baited traps confirmed the ester as an aggregation pheromone in Kenyan field trials, capturing both sexes of C. elongata and multiple associated pest or natural-enemy species.

The same study reported that pheromone-baited traps confirmed the ester as an aggregation pheromone in Kenyan field trials, capturing both sexes of C. elongata and multiple associated pest or natural-enemy species.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

A 2014 microbiology abstract identified 2-methylbutyl 2-methylbutanoate among fruity aroma esters excreted by Myroides sp. ZB35, described by the authors as the first finding of these esters in bacteria.

A 2014 microbiology abstract identified 2-methylbutyl 2-methylbutanoate among fruity aroma esters excreted by Myroides sp. ZB35, described by the authors as the first finding of these esters in bacteria.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Recorded dermal reference20%

A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.

unverified reference · No source provenance attached
No constituent-specific aromatherapy dermal limit was verified in this pass.
not specifiedRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Good Scents lists an IFRA-linked recommendation of up to 5.0000% in fragrance concentrate, which is a formulation-use reference and not a direct leave-on wellness recommendation.
not specifiedRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

The accessible evidence base for safety is light at the constituent-specific level; most archive confidence here should stay with identity and odor data rather than topical-use claims.
not specifiedRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

Aggregation pheromone signaling

A 2024 field-and-GC-EAD study identified 2-methylbutyl 2-methylbutanoate as a male-specific volatile from Clavigralla elongata and showed antennal detection by both sexes and a parasitoid natural enemy.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

No direct public citation is attached to this entry.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
  • No direct human clinical or consumer topical-use studies specific to 2-methylbutyl 2-methylbutanoate were found in this pass.
  • Most accessible evidence concerns aroma identity, occurrence, or insect semiochemistry rather than wellness mechanisms.
  • A fully readable constituent-specific toxicology assessment was not verified during this pass.
  • The numeric dermal reference lacks source provenance; a verified flag alone is insufficient.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (6)