3-Octanone

CAS:
106-68-3
Family:
aliphatic ketone
Also:
3-Octanone, ethyl amyl ketone, n-amyl ethyl ketone, octan-3-one

Found heavily in (9 oils total)

Also occurs in 1 other oils
Recorded sensory reference values
  • Affect valence: 0.4
  • Affect arousal: 0.1

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

3-Octanone is an aliphatic ketone found in some aromatic plants and fungal volatile profiles. In aroma materials it is mainly discussed for its herbaceous-fruity, mushroom-like character and for niche flavor or fragrance use. Early-stage biological literature also describes it as a semiochemical-style volatile in fungal systems, but those findings are preclinical and should not be read as human-use benefit claims.

Aroma and practical use

herbaceousfruityslightly spicybutterymushroom-likebanana-like
  • Use the recorded herbaceous, fruity, slightly spicy, buttery, mushroom-like, banana-like descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

A 2023 snail-control study reported that low concentrations of 3-octanone attracted brown garden snails, while higher concentration was repellent; the tested material also showed toxicity, supporting a possible lure-and-kill agricultural use case.

A 2023 snail-control study reported that low concentrations of 3-octanone attracted brown garden snails, while higher concentration was repellent; the tested material also showed toxicity, supporting a possible lure-and-kill agricultural use case.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

A reviewable PMC study summary on Metarhizium brunneum VOCs reported that 3-octanone influenced entomopathogenic nematode behavior, with high doses repelling or killing infective juveniles.

A reviewable PMC study summary on Metarhizium brunneum VOCs reported that 3-octanone influenced entomopathogenic nematode behavior, with high doses repelling or killing infective juveniles.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.

JECFA/FEMA flavor evaluation lists 3-octanone as having no safety concern at current levels of intake when used as a flavoring agent.
regulatoryRoute not recorded

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

No direct public citation is attached to this entry.

A peer-reviewed RIFM fragrance safety assessment exists, but only the abstract-level citation was accessible during this batch; fragrance-specific conclusions should therefore be treated as incompletely verified here.
industry safety reviewRoute not recorded

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

No direct public citation is attached to this entry.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

Volatile semiochemical signaling

The best-supported mechanism in the located literature is ecological rather than therapeutic: 3-octanone behaves as a volatile cue that can attract, repel, or intoxicate target organisms depending on concentration and species.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

No direct public citation is attached to this entry.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (4)
  • Full-text RIFM assessment confirms no safety concern for skin sensitization (read-across analog 2-heptanone, CAS 110-43-0) and that 3-octanone is not expected to be phototoxic/photoallergenic (evaluated via UV/Vis spectra), but it does not publish an explicit numeric dermal-limit percentage, so that value remains unconfirmed.
  • Most non-sensory biological findings are ecological or agricultural preclinical studies rather than human-focused data.
  • No constituent-specific numeric dermal reference is available here.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (7)