Artemisia ketone is an irregular monoterpene ketone found across wormwood, yarrow, santolina, and Artemisia annua chemotypes. The strongest live evidence supports its identity, odor profile, chemotype significance, and biosynthetic context, with a smaller amount of constituent-level fragrance-safety and assay-related evidence. Archive summaries should keep claims narrow: artemisia ketone is a useful marker constituent with early-stage research relevance, not a clinically validated active.
Chemical identity and composition
PubChem and NIST align artemisia ketone with formula C10H16O and CAS 546-49-6. NIST and PubChem also list isoartemisia ketone as a synonym, reflecting naming overlap that appears in aroma and essential-oil literature. The archive already tracks this constituent in wormwood, yarrow, and santolina-related oils.
Aroma and practical use
- Use the recorded herbal, honeyed, minty, berry-like, herbaceous, honey-like descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
artemisia chemotype marker
NIST and archive oil records support artemisia ketone as a defined monoterpene ketone present in wormwood and yarrow-related oils, with archive entries placing it from low-single-digit percentages to chemotype-level prominence depending on oil source.
Measured: identity, synonym, and occurrence support
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
biosynthetic marker
A PubMed-indexed biosynthesis paper specifically examined artemisia ketone formation in tansy and positioned it as an irregular monoterpene produced through specialized plant isoprenoid metabolism.
Measured: biosynthetic origin of artemisia ketone
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
mixture level antioxidant antimicrobial context
A recent full-text Artemisia annua oil study reported strong antioxidant and antimicrobial activity for the whole essential oil while identifying artemisia ketone among its principal constituents, supporting only mixture-level context for this compound.
Measured: mixture antioxidant and antimicrobial assays
This experimental finding does not establish benefit, dose or safety in people using this blend.
Use concerns and concentration limits
Sensitization concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.
unverified reference · No source provenance attachedThe Good Scents Company categorizes artemisia ketone as a flavor and fragrance agent and reports a fragrance-concentrate usage recommendation up to 0.8%, which is useful reference context but not a leave-on therapeutic-use standard.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Good Scents also links EFSA genotoxicity review material for alpha,beta-unsaturated ketones, so any safety interpretation should stay conservative rather than assuming broad unrestricted use.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
No human clinical safety studies specific to isolated artemisia ketone were verified in this pass.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
irregular monoterpene biosynthesis
A Phytochemistry study investigated labeling patterns in Tanacetum vulgare and described the biosynthesis of artemisia ketone as part of irregular monoterpene formation rather than standard head-to-tail terpene assembly.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
- Most accessible biological evidence is oil-level rather than isolated-compound evidence.
- No human clinical efficacy or constituent-specific dermal monograph was verified in this pass.
- Future upgrades should prioritize primary toxicology and isolated antimicrobial or antioxidant studies specific to pure artemisia ketone.
- The numeric dermal reference lacks source provenance; a verified flag alone is insufficient.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.