Cedrenol is a cedarwood-type sesquiterpene alcohol most often encountered in composition tables, perfumery references, and cedar-related natural-product chemistry rather than in direct human pharmacology. Live source checks support its identity, CAS number, fragrance-review status, and occurrence in Chinese cedarwood-style and other plant volatile profiles, but isolated mechanism and efficacy evidence remains sparse. For AromaForge, cedrenol is best presented as a woody cedar-marker alcohol with limited constituent-specific biological literature and clearly labeled evidence gaps.
Chemical identity and composition
PubChem resolves cedrenol to CID 119831 with formula C15H24O and a cedrane-type alcohol skeleton. CAS Common Chemistry confirms CAS 28231-03-0. In the local archive, cedrenol is already recorded at 6.1% in the Chinese Thuja cedarwood profile, and published GC-MS occurrence papers also report cedrenol among notable plant volatile constituents outside classic cedar oils.
Aroma and practical use
- Use the recorded woody, cedarwood, soft, dry, cedar-like, sesquiterpenic descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
microbial conversion from alpha cedrene
A 1993 Applied and Environmental Microbiology paper reported that a Rhodococcus strain catalyzed allylic oxidation of alpha-cedrene to produce (R)-10-hydroxycedrene, described as sec-cedrenol, in high yield.
Measured: regiospecific biotransformation product formation
This experimental finding does not establish benefit, dose or safety in people using this blend.
occurrence in chinese cedarwood profile
The local archive source for Chinese Thuja cedarwood lists cedrenol at 6.1% in the reviewed composition profile, supporting its role as a real but secondary oxygenated marker in that oil type.
Measured: relative abundance
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
occurrence outside cedarwood
A 2002 GC-MS paper on Anemone altaica essential oil reported cedrenol at 23.69%, showing that cedrenol can also appear as a major constituent in non-cedar aromatic plant materials.
Measured: relative abundance
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
Use concerns and concentration limits
Sensitization concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.
recorded reference · Fragrance material review on cedrenol, Food Chem Toxicol (2008), PubMed 18640179 - maximum skin level 3.15% in fine-fragrance formulae per IFRA 2004, assuming fragrance oil use up to 20% in finished product.A published fragrance-material review exists for cedrenol, but no open constituent-specific dermal-limit summary or modern human tolerability trial was verified in this pass.
The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.
No direct public citation is attached to this entry.
Because the accessible literature is dominated by occurrence data and one biotransformation paper, benefit-style copy for isolated cedrenol would overstate the evidence base.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
microbial biotransformation product
A classic microbiology paper described sec-cedrenol as the regiospecific allylic-oxidation product of alpha-cedrene formed by a Rhodococcus strain, placing cedrenol in a metabolic-conversion context rather than a human mechanism context.
This experimental finding does not establish benefit, dose or safety in people using this blend.
No direct public citation is attached to this entry.
no human validated mechanism
No constituent-specific human receptor, pharmacokinetic, or clinical mechanism for isolated cedrenol was verified in this pass.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (4)
- No human clinical studies specific to isolated cedrenol were verified in this pass.
- Direct mechanism and efficacy literature for cedrenol is sparse and is outweighed by occurrence, perfumery, and biotransformation references.
- The 2008 fragrance material review on cedrenol (PubMed 18640179) reports a maximum skin level of 3.15% in fine-fragrance formulae (IFRA, 2004) and notes terpene alcohols are not expected to elicit phototoxicity/photoallergy, but did not clearly report a quantified skin-sensitization outcome, so sensitizing was corrected from an unsourced true to null rather than left as a guess.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.