Coumaran (2,3-dihydrobenzofuran)

CAS:
496-16-2
Family:
dihydrobenzofuran (oxygen heterocycle)
Also:
Coumaran (2,3-dihydrobenzofuran)

Coumaran (2,3-dihydrobenzofuran) is a dihydrobenzofuran (oxygen heterocycle) occurring as a minor constituent of essential oils.

Aroma and practical use

No aroma description is attached to this identity yet.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

There are no constituent-specific outcome findings in this report. No therapeutic benefit is inferred from its presence.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Model screening value0.1%

Screening assumption (unknown default). It is not a verified constituent-specific exposure limit.

model fallback · Threshold of Toxicological Concern (TTC) applied to fragrance materials; Kroes/Munro framework

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (4)
  • Minor/trace constituent; full profile and SEO detail pending. Web search (2026-07-11) did not locate an IFRA standard or RIFM/Tisserand dermal-limit assessment specific to coumaran (2,3-dihydrobenzofuran, CAS 496-16-2); no_dermal_restriction:true and sensitizing:false remain unverified carryovers rather than citation-backed determinations. Follow-up web search (2026-07-13, queries: 'coumaran 2,3-dihydrobenzofuran CAS 496-16-2 IFRA fragrance safety dermal' and 'coumaran goodscentscompany 496-16-2 safety data') again found only generic supplier/MSDS/NIST WebBook pages and a RIFM assessment for the unrelated compound coumarin (CAS 91-64-5, not coumaran); no coumaran-specific IFRA/RIFM dermal-limit, sensitization, or phototoxicity determination was located. dermal_limit_source has been corrected from a mislabeled PubChem identity citation to null, and no_dermal_restriction has been corrected from an unsupported true to false since no source actually confirms an unrestricted-use determination.
  • No constituent-specific outcome findings are available in this report.
  • No cited aroma description is available for this identity.
  • No constituent-specific numeric dermal reference is available here.
All public references (1)