(E)-alpha-Atlantone is the exact trans isomer of alpha-atlantone associated with Atlas and Himalayan cedarwood oils. The reviewed evidence base is strongest for identity, cedarwood occurrence, and odor-analysis context rather than for direct human pharmacology: public sources describe it as a recurrent cedarwood ketone, document it in both Atlas and Himalayan cedarwood profiles, and include one odor-focused study showing that atlantones were not the main odor-impact compounds in Atlas cedarwood oil. No human clinical evidence or public constituent-specific dermal-limit data were verified in this pass.
Chemical identity and composition
NIST lists (E)-alpha-atlantone with formula C15H22O, InChIKey OJEFBZMKKJTKKK-JLHYYAGUSA-N, and CAS 108645-54-1. In the AromaForge archive it is already used as the exact constituent identifier in several cedarwood oil files, including an Atlas cedarwood profile with a 4.2-12.4% range and a Himalayan cedarwood profile listing 8.6%.
Aroma and practical use
- Use the recorded woody, dry cedar, cedar-like descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
atlas cedarwood occurrence range
A Journal of Essential Oil Research record summarized by AGRIS reports (E)-alpha-atlantone among the major Atlas cedarwood constituents, spanning 5.2-29.5% across analyzed samples.
Measured: relative abundance range
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
odor contribution reassessment
A Phytochemistry abstract reported that atlantones were odorless in the assay used by 12 panelists, whereas other cedarwood constituents produced the strongest odor-active signals.
Measured: odor-impact ranking
This experimental finding does not establish benefit, dose or safety in people using this blend.
Use concerns and concentration limits
Sensitization concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.
No public IFRA-style constituent-specific leave-on limit, phototoxicity warning, or human tolerability study was verified for isolated (E)-alpha-atlantone in the sources reviewed here.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Because the accessible literature is centered on composition and odor analysis rather than isolated toxicology, safety claims for this constituent should stay minimal and non-quantified.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
olfactory role reassessment
Atlas cedarwood GC-O and aroma extract dilution analysis ranked vestitenone and 4-acetyl-1-methylcyclohexene as stronger odor-active components, while atlantones were reported as odorless in that assay, indicating a composition marker role more than a dominant odor-impact role.
This experimental finding does not establish benefit, dose or safety in people using this blend.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (6)
- No human clinical studies specific to isolated (E)-alpha-atlantone were located in the reviewed public sources.
- Public evidence reviewed here did not provide constituent-specific dermal sensitization, phototoxicity, or numeric leave-on restriction data.
- Most accessible literature treats this molecule as a cedarwood identity and odor-analysis constituent rather than a standalone pharmacology subject.
- dermal_limit_pct corrected from an unsourced 2 to null (2026-07-13): whole-oil Cedarwood Atlas has no IFRA restriction and no regulated allergens (per IFRA conformity certificates), but no isomer-specific numeric leave-on limit for isolated (E)-alpha-atlantone (CAS 108645-54-1) was located.
- No constituent-specific numeric dermal reference is available here.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.