(E)-Tagetenone is an acyclic monoterpene ketone, also called trans-ocimenone, that appears as a characteristic component of Tagetes and related aromatic oils. The public evidence base is strongest for identity and occurrence in marigold-type chemotypes, while isolated constituent pharmacology and safety data remain sparse. Most biological claims in the accessible literature are still mixture-level findings from tagetes essential oils rather than direct standalone studies on purified (E)-tagetenone.
Chemical identity and composition
NIST lists (E)-tagetenone as C10H14O with CAS 33746-72-4 and synonyms including trans-tagetenone and (E)-ocimenone. Archive oil records place it in Tagetes minuta and related marigold materials, where it helps define a sharp green-herbal ketonic profile alongside dihydrotagetone and cis-tagetenone.
Aroma and practical use
- Use the recorded green, herbal, fruity, marigold-like, herbaceous descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
A 1996 Turkish Tagetes minuta oil paper reported (E)-tagetenone at 15.35% among the major constituents.
This is a clear early occurrence anchor for the constituent in marigold oil.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
A 2023 anti-quorum-sensing paper described Tagetes minuta essential oil containing trans-tagetenone at 23.1% and reported inhibition of biofilm-related virulence behavior.
The study supports relevance of trans-tagetenone-rich oils, but not a purified-compound claim.
This experimental finding does not establish benefit, dose or safety in people using this blend.
A 2023 Chincho (Tagetes elliptica) study reported trans-tagetenone at 18.84% in an oil that showed antibacterial and antioxidant activity.
This is another mixture-level signal rather than constituent-isolation evidence.
This experimental finding does not establish benefit, dose or safety in people using this blend.
Use concerns and concentration limits
Sensitization concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.
unverified reference · No source provenance attachedPublic constituent-specific oral, dermal, and inhalation toxicology appear thin; accessible summary databases explicitly note those toxicity values as not determined.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
I did not verify a public aromatherapy-style dermal maximum for isolated (E)-tagetenone in this pass.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Because current evidence is mostly mixture-level, any wellness or antimicrobial framing should stay tied to tagetes oils rather than to standalone medical-style claims for purified trans-tagetenone.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
no constituent-specific mechanism verified in this pass
The accessible literature ties trans-tagetenone mainly to active Tagetes oil chemotypes, but I did not verify a direct isolated-compound target or metabolic mechanism from a primary source.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
- I did not verify a direct isolated-compound pharmacology paper assigning a specific target or mechanism to purified (E)-tagetenone.
- Constituent-specific dermal, inhalation, and oral safety data remain sparse in the public sources reviewed here.
- Most accessible biological findings concern tagetes essential oils with trans-tagetenone as a major component, not purified trans-tagetenone itself.
- The numeric dermal reference lacks source provenance; a verified flag alone is insufficient.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.