Ethyl salicylate

CAS:
118-61-6
Family:
aromatic salicylate ester
Also:
Ethyl salicylate, benzoic acid, 2-hydroxy-, ethyl ester, ethyl 2-hydroxybenzoate, ethyl o-hydroxybenzoate

Found heavily in (3 oils total)

Recorded sensory reference values
  • Affect valence: 0.5
  • Affect arousal: 0.35

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

Ethyl salicylate is an aromatic salicylate ester with a sweet wintergreen-like odor used in fragrance and flavor contexts. The live literature is strongest for identity data, fragrance-safety review, and trace occurrence in wintergreen-style oils, while direct constituent-specific wellness evidence is sparse. AromaForge should therefore present Ethyl salicylate as a salicylate odorant with established safety-review attention but limited standalone efficacy literature.

Aroma and practical use

sweetwintergreen-likebalsamicfruity floral
  • Use the recorded sweet, wintergreen-like, balsamic, fruity floral descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

A 2022 analysis of commercial wintergreen essential oils reported Ethyl salicylate among the volatile constituents present in both Nepal and China samples.

A 2022 analysis of commercial wintergreen essential oils reported Ethyl salicylate among the volatile constituents present in both Nepal and China samples.

occurrence studyRoute not recordedOccurrence-focused analytical study.

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

A 2024 RIFM fragrance ingredient safety assessment reviewed Ethyl salicylate across toxicology endpoints including genotoxicity, repeated-dose toxicity, reproductive toxicity, photoirritation, and skin sensitization.

A 2024 RIFM fragrance ingredient safety assessment reviewed Ethyl salicylate across toxicology endpoints including genotoxicity, repeated-dose toxicity, reproductive toxicity, photoirritation, and skin sensitization.

safety reviewRoute not recordedModern safety-review paper.

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

An earlier 2007 fragrance material review specifically described Ethyl salicylate as the subject of toxicological and dermatological review when used as a fragrance ingredient.

An earlier 2007 fragrance material review specifically described Ethyl salicylate as the subject of toxicological and dermatological review when used as a fragrance ingredient.

safety reviewRoute not recordedEarlier safety-review benchmark.

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.

Ethyl salicylate has at least two dedicated RIFM/food-chemical-toxology review records, including a 2024 safety assessment and a 2007 fragrance material review.
safety reviewRoute not recorded

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

Because Ethyl salicylate is a salicylate ester, safety wording should stay alert to broader salicylate-sensitivity context without implying that its hazard profile is identical to methyl salicylate-rich wintergreen oil.
inferenceRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

This pass did not verify a public constituent-specific dermal maximum, phototoxicity limit, or human clinical trial for isolated Ethyl salicylate.
gap noteRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

salicylate-ester toxicology relevance

Safety literature treats Ethyl salicylate as a salicylate fragrance ingredient requiring toxicological and dermatological assessment, but this pass did not verify a constituent-specific human pharmacology mechanism beyond that safety framework.

safety reviewRoute not recorded

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
  • No strong human clinical efficacy literature specific to isolated Ethyl salicylate was verified in this pass.
  • Most accessible evidence is identity, trace occurrence, and safety review rather than mechanism or benefit studies.
  • No IFRA Standard exists for ethyl salicylate despite two dedicated RIFM/fragrance-material reviews (2007, 2024), so no category-specific dermal maximum could be sourced; the public RIFM records are more useful for cautious safety framing than for detailed consumer-facing use limits.
  • No constituent-specific numeric dermal reference is available here.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (6)