Lavandulol

CAS:
498-16-8
Family:
monoterpene alcohol
Also:
5-methyl-2-(1-methylethenyl)-4-hexen-1-ol, Lavandulol

Found heavily in (11 oils total)

Also occurs in 3 other oils
Recorded sensory reference values
  • Affect valence: 0.6
  • Affect arousal: 0.4

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

Lavandulol is an irregular monoterpene alcohol associated with true lavender and selected lavandin profiles, where it helps build the softer floral-herbal character of the oil. The strongest live evidence is for identity, enantiomer-specific odor quality, plant biosynthesis, and fragrance-safety assessment rather than for standalone therapeutic effects. AromaForge should treat lavandulol primarily as a lavender-marker aroma constituent with biosynthetic importance and limited direct human efficacy literature.

Chemical identity and composition

PubChem identifies the specific natural-leaning record as (-)-lavandulol, an irregular monoterpene alcohol rather than a standard head-to-tail monoterpene. A 2013 JBC paper showed that lavender biosynthesizes lavandulol derivatives through lavandulyl diphosphate synthase, which helps explain why lavandulol and lavandulyl acetate behave as distinctive lavender markers instead of generic terpene alcohols.

Aroma and practical use

floralherbalfreshcitrus-fruitylavender-likeherbaceous
  • Use the recorded floral, herbal, fresh, citrus-fruity, lavender-like, herbaceous descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Review the flagged use concerns across every contributing oil and the selected dilution.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

A 2005 study reported that the nature-identical (R)-lavandulol had stronger and more attractive floral-herbal citrus odor character than the unnatural (S)-enantiomer or the racemate.

A 2005 study reported that the nature-identical (R)-lavandulol had stronger and more attractive floral-herbal citrus odor character than the unnatural (S)-enantiomer or the racemate.

sensoryRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

A 2013 JBC paper functionally characterized lavandulyl diphosphate synthase from Lavandula x intermedia and showed that it specifically catalyzed formation of lavandulyl diphosphate, the precursor feeding lavandulol and lavandulyl acetate biosynthesis.

A 2013 JBC paper functionally characterized lavandulyl diphosphate synthase from Lavandula x intermedia and showed that it specifically catalyzed formation of lavandulyl diphosphate, the precursor feeding lavandulol and lavandulyl acetate biosynthesis.

biochemicalRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

A 2025 yeast-engineering study achieved 308.92 mg/L lavandulol production in fed-batch fermentation, reinforcing that lavandulol is a distinct industrial fragrance target with a defined biosynthetic route.

A 2025 yeast-engineering study achieved 308.92 mg/L lavandulol production in fed-batch fermentation, reinforcing that lavandulol is a distinct industrial fragrance target with a defined biosynthetic route.

biotechRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

Use concerns and concentration limits

Sensitization concernFlagged

Flagged in the constituent reference; assess the source, route and finished-product concentration.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Recorded dermal reference20%

A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.

unverified reference · No source provenance attached
A 2024 RIFM safety assessment concluded that the existing information supports current fragrance use of lavandulol and did not identify a genotoxicity concern in the reviewed dataset.
safety reviewRoute not recorded

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

No direct public citation is attached to this entry.

The accessible public literature for lavandulol is much stronger on identity, odor, and manufacturing than on direct human efficacy or clinical outcomes.
evidence synthesisRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

lavandulyl diphosphate synthase pathway

A lavender biochemical study identified lavandulyl diphosphate synthase as the enzyme catalyzing head-to-middle condensation of two dimethylallyl diphosphate units to lavandulyl diphosphate, the direct precursor to lavandulol and its derivatives.

biochemicalRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

enantiomer-specific odor expression

An odor study found the nature-identical R-enantiomer carried the strongest floral-herbal citrus nuance, while the S-enantiomer was described as very weak, supporting stereochemistry-dependent sensory impact.

sensoryRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
  • This pass did not verify a strong isolated-lavandulol human clinical literature base suitable for benefit-facing copy.
  • Most direct lavandulol literature is chemistry, odor, biosynthesis, or manufacturing oriented rather than pharmacology oriented.
  • A constituent-specific public dermal-use threshold for lavandulol was not verified in the reviewed sources.
  • The numeric dermal reference lacks source provenance; a verified flag alone is insufficient.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (6)