Propyl tiglate

CAS:
61692-83-9
Family:
aliphatic ester
Also:
Propyl 2-methylcrotonate, Propyl tiglate, n-Propyl tiglate, propyl (E)-2-methylbut-2-enoate

Found heavily in (5 oils total)

Recorded sensory reference values
  • Affect valence: 0.55
  • Affect arousal: 0.45

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

Propyl tiglate is a small aliphatic tiglate ester best documented in AromaForge as a Roman chamomile marker constituent and in flavor-fragrance references as a green, fruity odor material. The live evidence base is strong for identity, odor description, and occurrence, but thin for isolated mechanism or wellness-style pharmacology. It is best presented as an aroma and composition constituent with practical formulation relevance and clear evidence gaps around direct toxicology and human-use studies.

Aroma and practical use

greenfruityapple-likeseedy
  • Use the recorded green, fruity, apple-like, seedy descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Review the flagged use concerns across every contributing oil and the selected dilution.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

The EMA assessment report on Chamaemelum nobile lists propyl tiglate at 12% in the volatile oil composition summary, placing it among the notable named esters in Roman chamomile oil.

The EMA assessment report on Chamaemelum nobile lists propyl tiglate at 12% in the volatile oil composition summary, placing it among the notable named esters in Roman chamomile oil.

reference dataRoute not recordedRegulatory composition summary for Roman chamomile.

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

A 2005 Journal of Food Protection study reported propyl tiglate among the major esters produced in cheese by certain Pseudomonas fragi strains, showing that the compound also appears in microbial food-volatiles research.

A 2005 Journal of Food Protection study reported propyl tiglate among the major esters produced in cheese by certain Pseudomonas fragi strains, showing that the compound also appears in microbial food-volatiles research.

occurrence studyRoute not recordedFood-volatiles occurrence study.

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

Use concerns and concentration limits

Sensitization concernFlagged

Flagged in the constituent reference; assess the source, route and finished-product concentration.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Recorded dermal reference20%

A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.

unverified reference · No source provenance attached
The Good Scents Company lists a fragrance-concentrate recommendation of up to 2.0000% for propyl tiglate, but this is trade-reference guidance rather than a full publicly readable toxicology monograph.
reference dataRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No public human safety study, constituent-specific dermal sensitization dataset, or standalone pharmacology paper for isolated propyl tiglate was verified in this pass.
gapRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

expected_ester_hydrolysis

As an aliphatic ester, propyl tiglate is expected to undergo carboxylesterase-mediated hydrolysis to tiglic acid and propanol; this is a chemistry-based inference rather than a direct constituent-specific metabolism study.

inferenceRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
  • No direct human or animal pharmacology study focused on isolated propyl tiglate was verified.
  • Mechanistic handling is inferred from general ester metabolism rather than direct testing on this compound.
  • Public constituent-specific dermal and inhalation safety evidence remains limited.
  • The numeric dermal reference lacks source provenance; a verified flag alone is insufficient.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (6)