(Z)-Tagetone is a characteristic Tagetes monoterpene ketone that helps give marigold oil its sharp green-herbal and fruity facets. The live source base is strongest for identity and occurrence data, with repeated GC-MS reports showing it as a meaningful component of Tagetes oils and one accessible isolated-compound paper reporting antioxidant and antifungal assays for (Z)-tagetone. That makes it useful in the archive mainly as a chemotype marker with limited direct preclinical evidence rather than a well-developed standalone therapeutic literature.
Chemical identity and composition
PubChem, NIST, and The Good Scents Company align on (Z)-tagetone as the 5Z isomer of 2,6-dimethylocta-5,7-dien-4-one with formula C10H16O. Archive oil context places it in Tagetes minuta and related Tagetes species at substantial percentages, and older composition papers often discuss it alongside dihydrotagetone and the ocimenone or tagetenone isomers as a defining part of the tagetes ketone profile.
Aroma and practical use
- Use the recorded green, herbal, tagetes-like, fruity, sharp, herbaceous descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
A 2019 paper on Tagetes minuta flower oil, (Z)-tagetone, and thiotagetone reported that isolated (Z)-tagetone showed antioxidant activity in ferric-reducing and lipid-peroxidation assays and inhibited mycelial growth of Sphaceloma ampelinum by about 80% at six days.
A 2019 paper on Tagetes minuta flower oil, (Z)-tagetone, and thiotagetone reported that isolated (Z)-tagetone showed antioxidant activity in ferric-reducing and lipid-peroxidation assays and inhibited mycelial growth of Sphaceloma ampelinum by about 80% at six days.
This experimental finding does not establish benefit, dose or safety in people using this blend.
A 2014 Yemen Tagetes minuta oil study identified (Z)-tagetone at 1.8% in the tested oil, which also showed MRSA, Candida albicans, antioxidant, and cytotoxic activity at the whole-oil level rather than as isolated tagetone proof.
A 2014 Yemen Tagetes minuta oil study identified (Z)-tagetone at 1.8% in the tested oil, which also showed MRSA, Candida albicans, antioxidant, and cytotoxic activity at the whole-oil level rather than as isolated tagetone proof.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Use concerns and concentration limits
Sensitization concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
A recorded constituent reference, not a recommended oil dilution. Product category, source applicability and all contributing oils must be checked before use.
unverified reference · No source provenance attachedThis pass did not verify a constituent-specific dermal maximum, phototoxicity threshold, or human safety study for isolated (Z)-tagetone.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Available benefit-facing evidence is in vitro or whole-oil literature, so archive copy should avoid implying established human efficacy.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
These are research candidates recorded in the interaction matrix. They do not add a proven-amplification bonus to the score.
(Z)-TagetenoneAmplification candidate
Candidate in the research matrix. A coefficient alone does not establish amplification at the dose, route or goal of your blend; no proven amplification is inferred from this row.
review · whole_oil
No source citation attached.
Read (Z)-Tagetenone report →How the effects were investigated
free-radical scavenging and lipid-peroxidation modulation in assay systems
The accessible isolated-compound paper evaluated (Z)-tagetone in FRAP and lipid-peroxidation assays, which supports assay-level antioxidant behavior without establishing in vivo outcomes.
This experimental finding does not establish benefit, dose or safety in people using this blend.
No direct public citation is attached to this entry.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (7)
- Direct literature on isolated (Z)-tagetone is sparse and much thinner than the whole-oil Tagetes literature.
- This pass did not verify a human study, a high-quality isolated-compound toxicology review, or a constituent-specific fragrance safety standard.
- Many accessible biological claims are attached to Tagetes oils or mixed metabolites rather than isolated (Z)-tagetone.
- The numeric dermal reference lacks source provenance; a verified flag alone is insufficient.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
- Interaction candidates lack an attached source citation and remain unqualified.
- Some findings lack a directly linked source; treat those entries as unverified research notes.