benzyl acetate

CAS:
140-11-4
Family:
aromatic ester
Also:
acetic acid benzyl ester, benzyl acetate, phenylmethyl acetate

Found heavily in (5 oils total)

Recorded sensory reference values
  • Affect valence: 0.7
  • Affect arousal: 0.5

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

Benzyl acetate is a sweet floral aromatic ester strongly associated with jasmine, ylang-ylang, and other flower absolutes or essential oils. In the AromaForge archive it is best understood as a high-value fragrance marker and benzenoid ester with good identity, occurrence, metabolism, and safety-review coverage, but much thinner constituent-specific human bioactivity evidence. The most defensible archive claims center on floral odor character, common occurrence in white-floral oils, and rapid hydrolysis to benzyl alcohol and benzoic-acid metabolites rather than direct wellness claims.

Chemical identity and composition

Benzyl acetate has formula C9H10O2 and is the acetate ester of benzyl alcohol. Open toxicokinetic reviews describe it as rapidly hydrolyzed by esterases to benzyl alcohol and acetate, after which the benzyl alcohol fraction is mainly oxidized to benzaldehyde and benzoic acid and then excreted largely as hippurate.

Aroma and practical use

sweetfloraljasmine-likefruityylang-like
  • Use the recorded sweet, floral, jasmine-like, fruity, ylang-like descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

IARC's monograph review states that benzyl acetate is a major volatile constituent of jasmine, ylang-ylang, hyacinth, gardenia, and several other floral materials.

The NCBI Bookshelf monograph lists multiple natural sources and frames benzyl acetate as a fragrance ingredient with widespread exposure by ingestion, skin application, and inhalation.

reference dataRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

The same monograph reports that benzyl acetate is rapidly hydrolyzed and that no unchanged benzyl acetate was detected in rat or mouse plasma in cited toxicokinetic work.

The Bookshelf text states that only metabolites were present in plasma and urine after experimental dosing, supporting a metabolism-first interpretation of the constituent.

mechanisticRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

Animal carcinogenicity signals depended on study design: gavage studies produced some tumor findings, while diet studies did not show increased neoplasms in rats or mice.

The IARC review concludes there is limited evidence in experimental animals and classifies benzyl acetate as not classifiable to humans, which is a more accurate framing than calling it simply safe or unsafe.

animalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.

Benzyl acetate has meaningful fragrance-industry safety review history, but accessible human constituent-specific pharmacology remains sparse.
regulatory reviewRoute not recorded

The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.

No direct public citation is attached to this entry.

Because intact benzyl acetate is rapidly hydrolyzed, interpretation of systemic effects often overlaps with benzyl alcohol and benzoic acid metabolism rather than the ester alone.
mechanisticRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Animal hazard interpretation is route- and dose-pattern-sensitive, so archive language should avoid oversimplified safety conclusions.
animalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

No direct public citation is attached to this entry.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

rapid esterase hydrolysis to benzyl alcohol and acetate

IARC and JECFA sources describe very rapid hydrolysis of benzyl acetate, limiting the persistence of the intact ester after absorption.

mechanisticRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

downstream oxidation to benzoic acid with glycine conjugation to hippurate

The major downstream disposition route runs through benzyl alcohol and benzoic acid to urinary hippurate, which is why safety interpretation often relies on shared benzenoid metabolism.

mechanisticRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
  • This pass did not verify a strong isolated human clinical literature for benzyl acetate beyond fragrance and safety-review contexts.
  • Most accessible mechanistic evidence concerns absorption, hydrolysis, and toxicology rather than positive constituent-specific functional effects.
  • Direct dermal or inhalation aroma-use studies in humans were not located in a publicly accessible primary source during this pass.
  • No constituent-specific numeric dermal reference is available here.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (6)