(E)-2-Decenal is a cilantro-signature unsaturated aldehyde that appears repeatedly in coriander leaf aroma and essential-oil studies, where it helps define the herb's sharp green, waxy character. The strongest accessible evidence supports identity, occurrence, fragrance/flavor relevance, and a small preclinical literature on membrane-active antimicrobial or pesticidal behavior. Human therapeutic evidence was not verified in this pass, so AromaForge copy should keep benefit-facing claims cautious and non-medical.
Chemical identity and composition
PubChem lists (E)-2-decenal as CID 5283345 with formula C10H18O and IUPAC name (E)-dec-2-enal. The PubChem synonym set includes both CAS 3913-81-3 and 3913-71-1; the AromaForge cilantro oil record currently uses 3913-81-3, while the 2022 RIFM safety assessment title uses 3913-71-1. Cilantro literature consistently treats trans-2-decenal as one of the dominant leaf aldehydes, and the archive cilantro-herb oil file places it at 29.87% typical with reported ranges up to about 63% in reviewed coriander sources.
Aroma and practical use
- Use the recorded green, fatty, waxy, citrus-peel-like, cilantro-like descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Review the flagged use concerns across every contributing oil and the selected dilution.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
A 1996 Journal of Agricultural and Food Chemistry cilantro composition paper reported (E)-2-decenal among the principal cilantro leaf oil constituents and search-accessible snippets show values reaching about 63% total ion current in some samples.
A 1996 Journal of Agricultural and Food Chemistry cilantro composition paper reported (E)-2-decenal among the principal cilantro leaf oil constituents and search-accessible snippets show values reaching about 63% total ion current in some samples.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
A 2002 Letters in Applied Microbiology study found that (E)-2-decenal belonged to a series of plant 2E-alkenals that caused rapid liposome leakage, supporting bacterial membrane perturbation as part of the antibacterial mechanism.
A 2002 Letters in Applied Microbiology study found that (E)-2-decenal belonged to a series of plant 2E-alkenals that caused rapid liposome leakage, supporting bacterial membrane perturbation as part of the antibacterial mechanism.
This experimental finding does not establish benefit, dose or safety in people using this blend.
A 2014 Planta Medica study on cilantro aldehydes reported in vitro antileishmanial activity for (E)-2-decenal, including an IC50 of 7.85 +/- 0.28 microg/mL against promastigotes and 2.47 +/- 0.25 microg/mL against axenic amastigotes, without reported THP-1 macrophage cytotoxicity in that assay system.
A 2014 Planta Medica study on cilantro aldehydes reported in vitro antileishmanial activity for (E)-2-decenal, including an IC50 of 7.85 +/- 0.28 microg/mL against promastigotes and 2.47 +/- 0.25 microg/mL against axenic amastigotes, without reported THP-1 macrophage cytotoxicity in that assay system.
This experimental finding does not establish benefit, dose or safety in people using this blend.
Use concerns and concentration limits
Sensitization concernFlagged
Flagged in the constituent reference; assess the source, route and finished-product concentration.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.
A 2022 RIFM fragrance safety assessment exists for 2-decenal, indicating that this constituent has undergone formal fragrance-industry toxicology review, but a public leave-on dermal maximum specific to AromaForge use was not verified in this pass.
The source assessment applies to its specified exposure and preparation; this entry is not an unrestricted-use clearance.
No direct public citation is attached to this entry.
Because (E)-2-decenal is an alpha,beta-unsaturated aldehyde with membrane-reactive behavior in preclinical assays, irritation or sensitization caution is more defensible than assuming it is an inert trace aroma material.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
No constituent-specific human clinical safety trial or phototoxicity study was directly verified in the public sources reviewed here.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
lipid membrane perturbation
A mechanistic antibacterial paper testing (E)-2-decenal within a 2E-alkenal series found rapid dye leakage from model phospholipid liposomes, supporting membrane disruption as one plausible mechanism behind microbicidal activity.
This experimental finding does not establish benefit, dose or safety in people using this blend.
No direct public citation is attached to this entry.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
- No human clinical efficacy evidence for isolated (E)-2-decenal was verified in this pass.
- A public constituent-specific topical maximum for aromatherapy-style finished products was not verified.
- The accessible coriander occurrence evidence is stronger for composition and odor impact than for isolated human-use safety outcomes.
- No constituent-specific numeric dermal reference is available here.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.