(E)-2-Undecenal is an unsaturated fatty aldehyde found in coriander leaf and related green-herb aroma systems, where it contributes a citrus-peel, fatty, and soapy note profile. The strongest public evidence for this constituent is identity and occurrence chemistry, supported by one direct preclinical paper on isolated cilantro aldehydes and a broader safety evaluation for C7-C12 alpha,beta-unsaturated aldehydes used in fragrance and flavor contexts. Human clinical evidence was not located in this pass, so AromaForge should present it as a chemically defined aroma constituent with limited but real preclinical activity signals and clear irritation-sensitization caution.
Chemical identity and composition
NIST lists the exact (E)-isomer with formula C11H20O, InChIKey PANBRUWVURLWGY-MDZDMXLPSA-N, and CAS 53448-07-0. In the current archive it appears in cilantro herb oil at 3.84%, and broader coriander literature repeatedly places it within the leaf aldehyde cluster that gives coriander its characteristic citrus-fatty-green profile.
Aroma and practical use
- Use the recorded fruity, orange peel, citrus, fatty, soapy descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Review the flagged use concerns across every contributing oil and the selected dilution.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
antileishmanial screen
Search-result and ResearchGate snippets for a Planta Medica paper report isolated (E)-2-undecenal among the more active cilantro aldehydes, with IC50 values of about 2.81 microg/mL against promastigotes and 4.71 microg/mL against axenic amastigotes.
Measured: growth inhibition
This experimental finding does not establish benefit, dose or safety in people using this blend.
postharvest cilantro volatility
A Journal of Agricultural and Food Chemistry snippet reports that 3 kGy irradiation lowered (E)-2-undecenal immediately after treatment, while 1-2 kGy samples were higher than controls by day 7, showing that this aldehyde is sensitive to postharvest handling.
Measured: relative volatile abundance
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
Use concerns and concentration limits
Sensitization concernFlagged
Flagged in the constituent reference; assess the source, route and finished-product concentration.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.
A 2022 Australian government evaluation for C7-C12 linear alpha,beta-unsaturated aldehydes includes 2-undecenal and identifies skin sensitization, skin irritation, possible repeated-dose liver effects at high concentrations, and in-vitro genotoxic potential as class concerns, while also noting that low fragrance-use concentrations are expected to be efficiently detoxified.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Because the reviewed safety evidence is mainly class-based rather than a constituent-specific human tolerability dossier for isolated (E)-2-undecenal, archive copy should avoid numeric dermal-limit claims.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
electrophilic alpha beta unsaturated aldehyde reactivity
(E)-2-Undecenal belongs to the alpha,beta-unsaturated aldehyde class, whose members are chemically electrophilic and can react with biological nucleophiles such as glutathione and protein thiols; this chemistry is part of why class-level safety reviews emphasize irritation and sensitization risk.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
- No human clinical studies specific to isolated (E)-2-undecenal were located in the reviewed public sources.
- No constituent-specific IFRA-style public safety monograph or validated leave-on dermal limit was verified for the exact (E)-isomer in this pass.
- Most direct bioactivity evidence located for this constituent was limited to in vitro or snippet-level reporting.
- No constituent-specific numeric dermal reference is available here.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.