Eudesma-5,11(13)-dien-8,12-olide B is a eudesmane-type sesquiterpene lactone reported as a notable oxygenated minor-to-secondary marker in Buddha wood oil from Eremophila mitchellii. The strongest live support is for its chemical identity and repeated GC-MS occurrence in Buddha wood rather than for standalone human-use pharmacology or safety testing. AromaForge should therefore describe it as a structurally defined Buddha wood lactone with limited direct bioactivity evidence and explicit research gaps.
Aroma and practical use
- Use the recorded woody, dry, bitter-herbal, sesquiterpenic descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Review the flagged use concerns across every contributing oil and the selected dilution.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
A 2025 REVIVE Buddha Wood GC/MS report listed Eudesma-5,11(13)-dien-8,12-olide B at 5.94% and the corresponding A peak at 0.39%, indicating that the B assignment can be a notable secondary marker in commercial Buddha wood oil.
A 2025 REVIVE Buddha Wood GC/MS report listed Eudesma-5,11(13)-dien-8,12-olide B at 5.94% and the corresponding A peak at 0.39%, indicating that the B assignment can be a notable secondary marker in commercial Buddha wood oil.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
A 2019 Lotus Garden Botanicals certificate listed Eudesma-5,11(13)-dien-8,12-olide B at 3.16% in Buddha wood oil, supporting repeat occurrence across batches.
A 2019 Lotus Garden Botanicals certificate listed Eudesma-5,11(13)-dien-8,12-olide B at 3.16% in Buddha wood oil, supporting repeat occurrence across batches.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
A Barefut/Essential Oil University Buddha wood chromatogram listed Eudesma-5,11(13)-dien-8,12-olide B at 5.43%, again showing that this lactone is reproducibly detectable in Eremophila mitchellii wood oil.
A Barefut/Essential Oil University Buddha wood chromatogram listed Eudesma-5,11(13)-dien-8,12-olide B at 5.43%, again showing that this lactone is reproducibly detectable in Eremophila mitchellii wood oil.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
Use concerns and concentration limits
Sensitization concernFlagged
Flagged in the constituent reference; assess the source, route and finished-product concentration.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.
No constituent-specific dermal limit, IFRA restriction, phototoxicity paper, or dedicated toxicology study was verified in this pass for Eudesma-5,11(13)-dien-8,12-olide B.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
Because the public evidence is chemistry-first and the constituent is a sesquiterpene lactone, copy should stay cautious and avoid implying established safety equivalence with better-studied fragrance ingredients.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
How the effects were investigated
sesquiterpene-lactone reactivity is plausible but unverified here
The alpha,beta-unsaturated lactone motif suggests possible electrophilic reactivity typical of some sesquiterpene lactones, but this pass did not verify a constituent-specific mechanism study for the Buddha wood B assignment, so the mechanism remains an inference only.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (6)
- A constituent-specific CAS number for the archive's B peak assignment was not directly verified in public registry sources during this pass.
- No direct human clinical literature was located for isolated Eudesma-5,11(13)-dien-8,12-olide B.
- No constituent-specific toxicology, dermal limit, or phototoxicity study was verified.
- Public evidence is notably stronger for occurrence in Buddha wood GC-MS reports than for mechanism or benefit claims.
- No constituent-specific numeric dermal reference is available here.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.