Junenol

CAS:
472-07-1
Family:
sesquiterpene alcohol
Also:
Eudesm-4(14)-en-6alpha-ol, Junenol

Found heavily in (4 oils total)

Recorded sensory reference values
  • Affect valence: 0.05
  • Affect arousal: 0.25

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

Junenol is a sesquiterpene alcohol found in several essential oils and propolis-type natural products, but the current evidence base is uneven. Publicly accessible data are strongest for identity, biosynthetic context, and occurrence as a marker constituent in some oils, including palo santo and Acritopappus confertus. Bioactivity signals exist, but they are usually reported for complex oils or mixtures rather than for purified junenol. For AromaForge, junenol is best framed as a chemistry and profiling constituent with early preclinical associations, not as a validated standalone active.

Chemical identity and composition

PubChem maps junenol to CID 6452077 with formula C15H26O and a sesquiterpene-alcohol eudesmane skeleton. Public synonym records link junenol to the older descriptor eudesm-4(14)-en-6alpha-ol and CAS 472-07-1. Within the archive it appears in palo santo essential oil at 1.55%, while recent botanical papers also describe (+)-junenol as a major or marker constituent in Acritopappus confertus and as an identified though minor constituent in other essential oils.

Aroma and practical use

woodydryterpenicresinousresin
  • Use the recorded woody, dry, terpenic, resinous, resin descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

A 2025 GC-MS and antimicrobial paper reported (+)-junenol as the main compound in all Acritopappus confertus specimens at 13-52% and proposed it as a chemical marker of that plant material from Chapada Diamantina.

A 2025 GC-MS and antimicrobial paper reported (+)-junenol as the main compound in all Acritopappus confertus specimens at 13-52% and proposed it as a chemical marker of that plant material from Chapada Diamantina.

reference dataRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

A 2024 Journal of Agricultural and Food Chemistry abstract linked junenol and caryophyllene oxide with phytotoxic effects observed in Copaifera oils and noted that isolated compounds behaved differently from the whole oils, implying synergy or interaction effects.

A 2024 Journal of Agricultural and Food Chemistry abstract linked junenol and caryophyllene oxide with phytotoxic effects observed in Copaifera oils and noted that isolated compounds behaved differently from the whole oils, implying synergy or interaction effects.

in vitroRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

A 2016 plant biochemistry paper reported the cloning and functional analysis of a 10-epi-junenol synthase from Inula hupehensis, adding direct biosynthetic evidence for a junenol-related sesquiterpene pathway.

A 2016 plant biochemistry paper reported the cloning and functional analysis of a 10-epi-junenol synthase from Inula hupehensis, adding direct biosynthetic evidence for a junenol-related sesquiterpene pathway.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.

No constituent-specific human safety study, IFRA limit, or modern dermal threshold for isolated junenol was verified in the reviewed public sources.
gapRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

The Good Scents identity page lists junenol as a fragrance-related material but does not provide a transparent toxicology dossier that would support consumer-safety conclusions on its own.
reference dataRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Because bioactivity signals are mostly indirect, archive copy should avoid antimicrobial, herbicidal, or metabolic claims for isolated junenol.
gapRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

sesquiterpene biosynthesis from fpp

A plant biochemistry study reported a 10-epi-junenol synthase that converts farnesyl diphosphate into a junenol-related sesquiterpene product, clarifying junenol's biosynthetic pathway context.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

No direct public citation is attached to this entry.

phytotoxic association signal

A 2024 phytotoxicity paper associated junenol with observed seed-germination inhibition in Copaifera oils, but the abstract explicitly notes differing activity after compound isolation and suggests mixture interactions matter.

in vitroRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

No direct public citation is attached to this entry.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
  • No human clinical studies specific to isolated junenol were verified in this pass.
  • Most accessible bioactivity evidence is indirect, mixture-based, or biosynthetic rather than direct pharmacology on purified junenol.
  • A transparent constituent-specific dermal or inhalation safety threshold for isolated junenol was not located in the reviewed public sources.
  • No constituent-specific numeric dermal reference is available here.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (7)