Columellarin is a sesquiterpene lactone (guaianolide-type) occurring as a minor constituent of essential oils.
Aroma and practical use
No aroma description is attached to this identity yet.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
There are no constituent-specific outcome findings in this report. No therapeutic benefit is inferred from its presence.
Use concerns and concentration limits
Sensitization concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Penetration enhancementNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (4)
- Minor/trace constituent; full profile and SEO detail pending. Web search (2026-07-11) did not return a dedicated PubChem/NIST page confirming a CAS number for columellarin (only the previously noted PubChem CID 91704079 record); no IFRA/Tisserand dermal limit or dedicated sensitization/phototoxicity assessment was located, so sensitizing:true remains an unverified carryover from the guaianolide sesquiterpene-lactone class default rather than a compound-specific citation. Follow-up web search (2026-07-13) located The Good Scents Company record for columellarin (CAS 66873-37-8, PubChem CID 91704079), which lists no GHS hazard classification found and dermal toxicity 'not determined', and explicitly states columellarin is 'not for fragrance use' / 'not for flavor use' (i.e., no IFRA/RIFM assessment exists because it is not a registered fragrance ingredient). CAS has been added from this source. The prior sensitizing:true guaianolide-class-default guess has no compound-specific citation and has been corrected to null pending real data.
- No constituent-specific outcome findings are available in this report.
- No cited aroma description is available for this identity.
- No constituent-specific numeric dermal reference is available here.