Eremophilene

CAS:
10219-75-7
Family:
sesquiterpene hydrocarbon
Also:
Eremophila-1(10),11-diene, Eremophilene, Eremophylene

Found heavily in (3 oils total)

Recorded sensory reference values
  • Affect valence: 0.1
  • Affect arousal: 0.3

Reference values depend on measurement conditions and do not describe an effective dose or the perception of a custom blend.

Eremophilene is an eremophilane-type sesquiterpene hydrocarbon found in blue cypress and other botanical volatile profiles in the AromaForge archive. The current source base is stronger for identity, occurrence, and biosynthetic or agrochemical research than for human wellness evidence. Publicly accessible evidence does include a modern engineered-yeast study reporting insect-repelling activity for (-)-eremophilene, but that remains preclinical and application-specific, so the archive should frame eremophilene primarily as a chemistry marker with early functional signals rather than a validated therapeutic ingredient.

Chemical identity and composition

PubChem REST data identifies eremophilene as CID 12309744 with formula C15H24 and IUPAC name (3R,4aR,5S)-4a,5-dimethyl-3-prop-1-en-2-yl-2,3,4,5,6,7-hexahydro-1H-naphthalene. PubChem synonym data and The Good Scents Company both support CAS 10219-75-7 and the synonym eremophylene. In the AromaForge archive, blue cypress records place eremophilene at 3.38% of a public Callitris intratropica monograph profile.

Aroma and practical use

woodydryherbaceoussesquiterpenic
  • Use the recorded woody, dry, herbaceous, sesquiterpenic descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
  • Read the route, preparation and experimental context before using a study finding to choose an oil.

Reported benefits and effects

Findings retain their study context. An animal or laboratory result describes that experiment.

occurrence in blue cypress

The reviewed Australian Botanical Products blue cypress monograph lists eremophilene at 3.38% among the principal sesquiterpenes of Callitris intratropica wood-and-bark oil.

reference dataRoute not recordedsupplier monograph transcription of steam-distilled blue cypress oil profile

Measured: principal constituent percentage

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

insect repellency research

The PubMed snippet for the 2022 Metabolic Engineering paper states that (-)-eremophilene repelled fall leafworm, positioning eremophilene as an early-stage agricultural or ecological research molecule.

preclinicalRoute not recordedengineered yeast production plus insect-repelling assay

Measured: repellency against fall leafworm

This experimental finding does not establish benefit, dose or safety in people using this blend.

Use concerns and concentration limits

Sensitization concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Phototoxicity concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Oxidation concernNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

Penetration enhancementNot flagged

Not flagged in the current model. This is not proof of absence or unrestricted safety.

No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.

The Good Scents Company lists eremophilene as a natural substance and extractive and notes 'not for fragrance use' and 'not for flavor use,' but does not provide a transparent constituent-specific dermal limit.
not specifiedRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

No human safety trials, constituent-specific sensitization reviews, or phototoxicity studies for isolated eremophilene were located in the reviewed public sources.
not specifiedRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Oil-level tolerability information for blue cypress should not be treated as direct safety proof for isolated eremophilene.
not specifiedRoute not recorded

This reference does not establish a therapeutic result or a safe use level for a custom oil blend.

No direct public citation is attached to this entry.

Constituents it may interact with

No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.

How the effects were investigated

insect repellent volatile signal

The accessible abstract literature links (-)-eremophilene to repellency against fall leafworm, suggesting a volatile ecological or pest-deterrent mechanism rather than a medical mechanism.

preclinicalRoute not recorded

This experimental finding does not establish benefit, dose or safety in people using this blend.

What this report cannot establish

  • A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
  • The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
  • An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
  • A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
  • Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (6)
  • No human clinical studies specific to isolated eremophilene were located in the reviewed public sources.
  • Direct constituent-specific anti-inflammatory, antimicrobial, or topical-use papers were not verified in this pass beyond ecological or engineering-context evidence.
  • Constituent-specific dermal-limit, sensitization, and phototoxicity data were not located in the reviewed public sources.
  • 2026-07-13 verification pass: web search for IFRA/RIFM dermal limit and sensitization data found no authoritative constituent-specific results; prior dermal_limit_pct (25) and sensitizing (true) were unsourced placeholders and have been corrected to null.
  • No constituent-specific numeric dermal reference is available here.
  • Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.
All public references (6)