alpha-Calacorene is a minor sesquiterpene hydrocarbon found in several essential oils and aromatic plant profiles, including calamus root in the AromaForge archive. The current public evidence base is strongest for chemical identity and analytical occurrence rather than for isolated human-use pharmacology. Archive-safe positioning is that alpha-calacorene is mainly a woody sesquiterpene marker with sparse standalone mechanism and safety literature, so any broader activity discussion should stay tied to mixed-oil or extract studies rather than framed as a direct medical claim.
Chemical identity and composition
PubChem lists alpha-Calacorene with molecular formula C15H20 and the stereochemical name (1S)-4,7-dimethyl-1-propan-2-yl-1,2-dihydronaphthalene. NIST lists CAS 21391-99-1 and related naming variants including Calacorene and (+)-alpha-Calacorene. In the archive's calamus root oil record, alpha-calacorene was reported at 0.56% by GC-MS.
Aroma and practical use
- Use the recorded woody, dry, sesquiterpenic descriptors to explore a blend's scent character; perceived strength also depends on the other ingredients.
- Review the flagged use concerns across every contributing oil and the selected dilution.
- Read the route, preparation and experimental context before using a study finding to choose an oil.
Reported benefits and effects
Findings retain their study context. An animal or laboratory result describes that experiment.
occurrence in calamus root
A reviewed calamus root GC-MS certificate used in the archive reported alpha-calacorene at 0.56% of the analyzed oil.
Measured: relative abundance
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
mixed oil antimicrobial context
A PubMed-indexed abstract reported alpha-calacorene at 4.97% in Teucrium montanum essential oil and described antibacterial and antifungal activity for the whole oil, but it did not isolate alpha-calacorene as the confirmed active constituent.
Measured: oil composition plus antibacterial and antifungal activity
This experimental finding does not establish benefit, dose or safety in people using this blend.
Use concerns and concentration limits
Sensitization concernFlagged
Flagged in the constituent reference; assess the source, route and finished-product concentration.
Phototoxicity concernNot flagged
Not flagged in the current model. This is not proof of absence or unrestricted safety.
Oxidation concernNot assessed
Not assessed in the available record.
Penetration enhancementNot assessed
Not assessed in the available record.
No numeric constituent-specific use limit is available here. Missing is not an unrestricted-use clearance.
No constituent-specific dermal limit, IFRA restriction, or phototoxicity study was located in the reviewed public sources for isolated alpha-calacorene.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Because direct toxicology literature is sparse, consumer-facing summaries should keep safety language conservative and avoid implying established tolerability for isolated alpha-calacorene.
This reference does not establish a therapeutic result or a safe use level for a custom oil blend.
No direct public citation is attached to this entry.
Constituents it may interact with
No constituent-pair interaction is recorded for this identity. The report does not assume either amplification or incompatibility.
What this report cannot establish
- A reported constituent percentage does not establish an effective human therapeutic dose or the amount absorbed into the body.
- The presence of a constituent does not guarantee a clinical benefit, rash treatment or sleep improvement from a custom blend.
- An unflagged concern or missing use limit does not establish safety for ingestion, inhalation, skin exposure or a particular person.
- A candidate constituent interaction does not establish that two oils amplify one another at the selected proportions.
- Constituent descriptors alone do not establish a precise top, heart or base lifetime in a finished blend.
Known data gaps (5)
- No human clinical studies specific to isolated alpha-calacorene were located in the reviewed public sources.
- No direct constituent-specific mechanism paper was located; accessible activity discussion is mostly indirect through mixed essential-oil or extract studies.
- Constituent-specific sensitization, dermal-limit, and phototoxicity data were not located in the reviewed public sources.
- No constituent-specific numeric dermal reference is available here.
- Some findings do not record an explicit exposure route; consult the linked study before applying them to a use.